Pausch was diagnosed with pancreatic cancer^[3][11] and underwent a Whipple procedure (pancreaticoduodenectomy) on September 19, 2006 in an unsuccessful attempt to halt his pancreatic cancer.^[12] He was told in August 2007 to expect a remaining three to six months of good health. He soon moved his family to Chesapeake, Virginia, a suburb near Norfolk, to be close to his wife's family. On March 13, 2008, Pausch advocated for greater federal funding for pancreatic cancer before the United States Senate Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies.^[13] In the week prior to this, he had been hospitalized in order to have needle aspiration of pleural effusion in his right lung.^[14]

On May 2, a Positron emission tomography (PET) scan showed that he had very tiny (5 millimetres (0.20 in) or less) metastasis in his lungs and some lymph nodes in his chest. He also had some metastases in his peritoneal and retroperitoneal cavities. On June 26, 2008, Pausch indicated that he was considering stopping further chemotherapy because of the potential adverse side effects. He was, however, considering some immuno-therapy-based approaches.^[15] On July 24, on behalf of Pausch, a friend anonymously posted a message on Pausch's webpage stating that a biopsy had indicated that the cancer had progressed further than what was expected from recent PET scans and that Pausch had "taken a step down" and was "much sicker than he had been". The friend also stated that Pausch had then enrolled in a hospice program designed to provide palliative care to those at the end of life.

 

I wouldn't suspect metastasis

Pausch died from pancreatic cancer at his family's home in Chesapeake, Virginia on July 25, 2008, having moved there so that his wife and children would be near family after his death. He is survived by his wife Jai, and their three children, Dylan, Logan and Chloe.^[16]