mucums membrane pemphigoid - An Autoimmune issues like blisters in the mouth

Synonyms

  • Benign Pemphigus
  • Old Age Pemphigus
  • Parapemphigus
  • Pemphigoid
  • Senile Dermatitis Herpetiformis

 

Bullous pemphigoid (BP) is a chronic, autoimmune, subepidermal, blistering skin disease that rarely involves mucous membranes. BP is characterized by the presence of immunoglobulin G (IgG) autoantibodies specific for the hemidesmosomal BP antigens BP230 (BPAg1) and BP180 (BPAg2).

emedicine.medscape.com/article/1062391-overview

Bullous pemphigoid is a rare, chronic condition in which fluid-filled blisters (bullae) erupt on the surface of your skin, usually on your arms, legs or trunk. The cause of bullous pemphigoid is unknown, but it's thought to be related to a disorder of the immune system.

mayoclinic.com/health/bullous-pemphigoid/DS00722

Bullous pemphigoid is a skin disorder characterized by large blisters.

The cause is unknown buy may be related to immune system disorders.

In severe cases, they are multiple blisters, called bullae. The blisters are usually located on the arms, legs, or middle of the body. About one-third of persons with bullous pemphigoid also develop blisters in the mouth. The blisters may break open and form ulcers or open sores

healthline.com/adamcontent/bullous-pemphigoid

 

Bullous Pemphigoid is a rare, autoimmune, chronic skin disorder characterized by blistering. This disorder occurs most frequently in elderly people. Generalized blistering occurs in and under the upper layers of the skin and usually subsides spontaneously within several months or years. However, symptoms may recur. In some rare cases of Bullous Pemphigoid, complications such as pneumonia may develop.

Resources

American Autoimmune Related Diseases Association, Inc.
22100 Gratiot Avenue
Eastpointe, MI 48021-2227
Tel: (586)776-3900
Fax: (586)776-3903
Tel: (800)598-4668
Email: aarda@aarda.org
Internet: http://www.aarda.org/

NIH/National Arthritis and Musculoskeletal and Skin Diseases Information Clearinghouse
1 AMS Circle
Bethesda, MD 20892-3675
USA
Tel: 3014954484
Fax: 3017186366
Tel: 8772264267
TDD: 3015652966
Email: NIAMSinfo@mail.nih.gov
Internet: http://www.niams.nih.gov/Health_Info

National Cancer Institute
6116 Executive Blvd, MSC 8322, Room 3036A
Bethesda, MD 20892-8322
USA
Tel: 3014353848
Tel: 8004226237
TDD: 8003328615
Internet: http://www.cancer.gov

AutoImmunity Community

Tel: (919)-55-2-9057
Email: bandrews@autoimmunitycommunity.org
Internet: http://autoimmunitycommunity.org

 

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders, Inc. (NORD). A copy of the complete report can be obtained for a small fee by visiting the NORD website. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational treatments (if available), and references from medical literature. For a full-text version of this topic, see     rarediseases.org/search/rdblist.html

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

 

Bullous pemphigoid is an autoimmune disease that causes blistering of the skin.

  • Bullous pemphigoid occurs when the immune system attacks the skin and causes blistering.
  • People develop large, itchy blisters with areas of inflamed skin.
  • Doctors can diagnose bullous pemphigoid by examining skin samples under a microscope and checking for certain antibody deposits.
  • Treatment involves corticosteroids and drugs that suppress the immune system.

 

Bullous pemphigoid tends to occur mainly in older people. It is a less serious disease than pemphigus, is rarely fatal, and does not result in widespread peeling of skin. It can involve a large portion of the skin, however, and can be very uncomfortable, with itchiness often the first sign of the disease.

In bullous pemphigoid, the immune system forms antibodies directed against the skin, resulting in large, tense, very itchy blisters surrounded by areas of red, inflamed skin. Blisters in the mouth are uncommon and are not severe. The areas of skin that are not blistered appear normal.

Diagnosis and Treatment

Doctors usually recognize bullous pemphigoid by its characteristic blisters. However, it is not always easy to distinguish it from pemphigus vulgaris and other blistering conditions, such as severe poison ivy. Bullous pemphigoid is diagnosed with certainty by examining a sample of skin under a microscope (skin biopsy). Doctors differentiate bullous pemphigoid from pemphigus vulgaris by noting the layers of skin involved and the particular appearance of antibody deposits.

merck.com/mmhe/sec18/ch209/ch209b.html

Dermatitis herpetiformis is an autoimmune disease causing clusters of intensely itchy small blisters and hivelike swellings. Diagnosis and Treatment

The diagnosis is based on a skin biopsy, in which doctors find particular kinds and patterns of antibodies in the skin samples.

The blisters do not go away without treatment. People are usually placed on a gluten-free diet (a diet that is free of wheat, rye, and barley). The drug dapsone, taken by mouth, almost always provides relief in 1 to 2 days but requires that blood counts be checked regularly. Once the disease has been brought under control with drugs and the person has followed a strict gluten-free diet for 6 months or longer, drug treatment usually can be discontinued. However, some people can never stop taking the drug. In most people, any reexposure to gluten, however small, triggers another outbreak. A gluten-free diet may prevent the development of intestinal lymphoma.

Dermatitis herpetiformis is not related to the herpesvirus

Despite its name, dermatitis herpetiformis has nothing to do with the herpesvirus. In people with dermatitis herpetiformis, glutens (proteins) in wheat, rye, and barley products somehow activate the immune system, which attacks parts of the skin and causes the rash and itching. People with dermatitis herpetiformis often have celiac sprue (see Malabsorption: Celiac Sprue), which is an intestinal disorder caused by sensitivity to gluten, although they may not have symptoms from the celiac sprue. People also have a higher incidence of other autoimmune diseases, such as thyroiditis, systemic lupus erythematosus, sarcoidosis, and diabetes. People with dermatitis herpetiformis occasionally develop lymphoma in the intestines.

 

 

Robin Crochet of Louisiana was a worker in 1989 at the Seward Seal recovery after the Exxon Valdez Oil Spill

at the end of the season when they brought out the beach cleanup chemicals ... Inipol EAP 22 (Harmful component 2-butoxyethanol)... they took in an orange furred baby seal.  It had mouth ulcers.  In a few days she and the other workers had mouth ulcers.  When they went to the doctors, they were told it was just a virus.  Later many other symptoms showed up and Robin died in 2005 after an operation in 2003 to remove her pancreas and spleen

This chemical won't do just one thing - If you only have one health issue, and/or your parent doesn't have 'the odd assortment of CFIDS symptoms,' don't suspect 2-butoxyethanol poisoning.

Compare EVOS Robin   to   Gulf War Vet Donny

Suspect Dec 1997 exposure