this fatigue lead to paralysis?
Fatigue - Prostate Cancer - Paralysis
I heard of paralysis happening to a painter (who died this past
2003 as a young man about 44). He was being seen for prostate
cancer, and he had pain in his back & bones, but didn't
get a diagnosis for that. Then he became paralyzed ... due to?
extramedullary hematopoiesis: red blood cell production
outside the vertebrae. Red blood cells are derived from the stem
cells in the bone marrow throughout the body. When individuals
become severely anemic, there is not enough space in the ctive
bone marrow to produce hemoglobin, and the body begins to make
blood outside the bone marrow: in the spleen, liver, and
sometimes outside the vertebrae, which can compress the spinal
cord, leading to paralysis
His family (after his death) said that he had all of the
symptoms of this chemical exposure, 2-butoxyethanol - (& of
course he was exposed to the chemical) but he didn't get an
accurate diagnosis - they didn't know what was happening with his
bones. Since there is a red blood cell anemia, I was wondering if
the above definition was part of what is happening to these ....
(either from very extreme, serious exposure to too much of the
chemical even in a brief exposure, or in many mini exposures over
a long period of time)?
correct diagnosis was that his red blood cell where
reproducing outside of the spine causing spinal
cord compression.. Once this happens you have a 72
hour slide period to have surgery to release the
compression or a bone marrow transplant. Maurice missed
this 72 hour period by two weeks. Because other oncologist
did not do his job well. Maurice was in Little co. of
Mary Hospital and this doctor came in the room and
pressed his hand on his back and said no pain no cancer
on back. I responded how could he feel pain he is on
morphine. The Dr. rudely turned to me and said he has a
few small cancer spots in his tummy and walked away"
The chemical that affects painters & many
others is 2-butoxyethanol
(a pesticide, solvent, poison). The first thing people notice who
are affected by it is all-the-time fatigue (red blood cell
damage) that no rest helps - No energy; then depression all the
time, personality changes to very grouchy, 'grumpy' - Extreme
Irritability, Loose temper easily, Short term memory loss,
Difficulty concentrating, Suicidal Tendencies, (many assorted central
nervous system diagnosis) ... endocrine disruption to
pituitary? to thyroid? to blood pressure? to blood sugar? to reproductive
organs? to adrenal glands? This chemical, also known as ethylene
glycol monobuytl ether, is known to cause hemolytic anemia, but I
have wondered why it is so hard to find. The red blood cell counts
come in borderline normal.
Then I realized that it takes awhile for the blood system to
get so bad that it shows up. The retic ratio should indicate if
there aren't enough mature red blood cells, shouldn't it?
These are symptoms of
One definition of Hemolytic anemia: At the end of their
normal life span (about 120 days), RBCs are removed by
components of the mononuclear phagocyte system, principally in
the spleen, where Hb catabolism takes place. The essential
feature of hemolysis is a shortened RBC life span; hemolytic
anemia results when bone marrow production can no longer
compensate for the shortened RBC survival.
- Pale color
- Shortness of breath
- Rapid heart rate
- Yellow skin color (jaundice)
- Dark urine (indicative of blood in urine - never dismiss
this! Stop exposure immediately!)
- Enlarged spleen
Concise International Chemical Assessment Document 10
2-Butoxyethanol This report contains the collective views of an
international group of...
for those who may need to check your blood in particular ways.
What ways? (Now with
links to definitions)
Back up definitions here:
reticulocyte: a young red cell (erythrocyte) released by
the bone marrow that contains no nucleus but has residual RNA;
normally composes about 1% of circulating blood cells. The
reticulocyte count is increased in hemolytic anemia.
Granulocytosis: an increase in the number of blood
granulocytes - compare LYMPHOCYTOSIS, MONOCYTOSIS Causes of
reactive granulocytosis include: Infection: Inflammatory ...
What are the major pathophysiologic mechanisms for
Elevation of the granulocyte count may result from a primary
bone marrow disorder resulting in autonomous proliferation of
cells or it may be a secondary response to an underlying
condition. There are a few, rare syndromes associated with
granulocytosis without an underlying cause.
erythrocytosis: an increase in the number of red cells in
the blood, esp. in response to a stimulus such as anemia. Erythropenia
(eh-REETH-ro-PEA-nee-uh) The condition of having abnormally low
numbers of red blood cells
leukocytes: all the white cells including: neutrophils,
lymphocytes, eosinophils, basophils, and monocytes. eukocytosis:
any condition in which the number of leukocytes or white cells
in the circulating blood is abnormally high; a white cell count
of 10,000 or more per cubic millimeter. This is a non-specific
finding. Generally when there is an increase in red cell
production, the white cell count is elevated. If there are many
immature red blood cells present in the circulation, the white
cell count as done by a machine is elevated. A 'corrected white
count' is then done manually with a microscope.
hemolysis: alteration, dissoultion, or destruction of red
blood cells in such a manner that hemoglobin is liberated. The
spleen normally filters the blood and removes abnormal red blood
cells. If most cells are normal, the amount of hemoglobin
released is easily metabolized by the liver and recycled by the
body. If there are large numbers of abnormal red cells, the
liver metabolizes the hemoglobin to bilirubin in quantities too
great to be quickly recycled and jaundice results.
Hematuria: Hematuria refers to the excretion of
abnormal quantities of Red Blood Cells (RBCs) into the urine.
... Causes of Hematuria. ... http://www.duj.com/hematuria.html
Hematuria is a clinical term referring to the presence of blood
in the urine
spleen: an organ in the upper left quadrant of the
abdomen that is important in immune function and in the
maintenance of normal red blood cell anatomy. The spleen is the
largest single immune organ in the body, playing a particularly
important role in clearing some bacteria from the blood during
infection. The spleen contains immune cells that activate the
immune system (T cells) and produce antibodies (B cells). Red
blood cells that are old or not normal in any other way are
disintegrated by the spleen, releasing hemoglobin. This
hemoglobin is converted to bilirubin by the liver and leads to
jaundice. If the spleen is required to remove more than the
usual red blood cells, it can become enlarged and increase its
function, leading to increased hemolysis and jaundice.
jaundice: a yellowish staining of the skin, the whites of
the eyes and deeper tissues caused by an increased presence of
bilirubin (bile pigments) in the plasma of the blood. This can
be a result of excessive breakdown of red blood cells or liver
disease such as hepatitis (also called icterus).
caused by excessive hemolysis -outside link
marrow: the part of the bone where the red and white
cells are produced. In normal adults there is a fat in the bone
marrow; in persons with anemia, the bone marrow is completely
filled primarily with red blood cell precursors.
renal: relating to, involving, affecting, or located in
the region of the kidneys
does the liver do?
Milk Thistle has been found helpful by
Along with kidneys, the liver is also a targeted organ of
pulmonary edema: abnormal accumulation of fluid in the
There is also eye damage with 2-butoxyethanol, skin
damage, damage to mucous membranes of sinuses, lungs, and
Present an abnormal blood picture showing: Erythropenia
Present an abnormal blood picture showing: Reticulocytosis
Present an abnormal blood picture showing: Granulocytosis
Present an abnormal blood picture showing: Leukocytosis
Likely to Cause Fragility of Erythrocytes
Likely to Cause Hematuria