... view of someone in France
... view of someone in France
GLYCOL ETHERS INFORMATION UPDATE
Proposes Delisting of Ethylene Glycol Butyl Ether (EGBE)
a Hazardous Air Pollutant
Protection Agency (EPA) announced on November 5, 2003 that it would
shortly be publishing in the Federal Register its proposal to delist
ethylene glycol butyl ether (EGBE) from the Clean Air Act Amendments' (CAAA)
list of Hazardous Air Pollutants (HAPs). An EPA decision to delist would
mean that EGBE would no longer be subject to the CAAA's Maximum
Achievable Control Technology (MACT) requirements, or its residual risk
and other requirements. EPA
will be receiving comments for 60 days after Federal Register
publication and will hold a public hearing if requested.
Chemistry Council Ethylene Glycol Ethers Panel (ACC Panel) filed a
petition in August 1997 showing why the available evidence indicated
that EGBE should be delisted. EPA
found the petition complete as of December 21, 1998, and sought comments
on the petition on August 3, 1999 (64 Fed. Reg. 42125).
All submitted comments supported the petition.
EPA is directed
under the CAAA to delist HAPs if there are "adequate data on the
health and environmental effects of the substance to determine that
emissions, ambient concentrations, bioaccumulation or deposition of the
substance may not reasonably be anticipated to cause any adverse effects
to human health or adverse environmental effects," Section
112(b)(3)(C). The Federal Register proposal (available at http://www.epa.gov/airlinks/airlinks1.html)
indicates the Agency has found the data on EGBE meets this standard.
EPA finds wide
margins of safety (“Hazard Quotients”) between estimated maximum
exposures and lowest toxicity effect levels.
Specifically, EPA states maximum human exposures will be 16 to 50
times lower than the lowest level expected to pose any risk to human
health. Thus, EPA concludes: “[W]e
judge that the potential for human health and environmental effects
[from EGBE] is sufficiently low to provide reasonable assurance that
such adverse effects will not occur.”
EPA also notes that
exposure estimates were “at least a factor of 2” higher than what
the Agency expects would be the maximum individual exposure and “at
least an order of magnitude” less than the Agency’s Reference
Concentration (RfC) (the level below which the Agency does not expect
any adverse health effects).
EPA also reviewed
the numerous toxicity studies of EGBE.
The proposal includes extensive Agency scientific interpretation
of all the toxicity studies (including lifetime animal studies that
investigated chronic effects including cancer).
The Agency finds these data fully support its RfC for EGBE issued
in 1999. EPA includes in
the proposal its most recent interpretation of the NTP study of cancer
in mice and rats and concludes that extensive data show that its 1999
RfC is “sufficient” to prevent any cancer risk to humans.”
For an historical
perspective of the delisting petition, please review the Information
Update on the Panel’s website (http://egep.org/delist6.htm).
Delisting of Ethylene Glycol Butyl Ether (EGBE) as a Hazardous Air
Pollutant — November 2003
This information is brought to you by the member companies
of the American Chemistry Council CHEMSTARâ Ethylene Glycol Ethers Panel: The Dow
Chemical Company, Eastman Chemical Company, Equistar Chemicals, LP, and
Shell Chemical Company. For
more information, please call your supplier representative, or Dr. Susan
A. Lewis, Manager of the EGE Panel at (703) 741-5635 or by E-Mail:
fair use Home Page for this info http://www.egep.org/index.shtml
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