valdezlink.com/walking_in_gods_armour.htm

Normal values for the SGOT and the SGPT vary from one clinical laboratory to another. As a result, I can give you the normal values for our lab but not for yours. However, it should be easy for you to call your doctor’s office and have her/his nurse or secretary give you these numbers because they are usually listed with you lab results. As a matter of fact, you might want to get a copy of your results so that you have them for your personal records.

Please let us know if you have any additional information or questions. You can post the material back to MedHelp. The direct number to our Liver Clinic at Henry Ford is (313) 916-8865.

This response is being provided for general informational purposes only and should not be considered medical advice or consultation. Always check with your personal physician when you have a question pertaining to your health

LIVER?

Elevations of SGPT, an enzyme found within the liver cells, indicate that the liver cells are either leaky (internal contents are entering the blood) or damaged. A wide array of conditions can cause this problem. For example, viral hepatitis or alcohol can cause elevated SGPT. We know that patients can have elevated liver tests as a result of fatty liver, a condition that does not necessarily mean generalized obesity. Usually fatty liver is not a cause for significant liver problems.

Lipitor can cause a drug-induced liver damage. Patients taking this medication must be monitored for elevations of liver tests.
 
CLINICAL Question

36 year-old caucasian male
Laparoscopic Cholecystectomy 5/94
Lab 1/13/04
RBC 2.93 L
HEMOGLOBIN 9.7 L
HEMATOCRIT 27.6 L
RDW 16.0 H
POLYS 38 L
GLUCOSE, SERUM 128 H
BILIRUBIN, TOTAL 2.4 H
AST 43 H
ALT 56 H
IRON BIND. CAP 185 L
UIBC 138 L
IRON SATURATION 25
SEDIMENTATION RATE-
WESTERGREN 28 H
FERRITIN, SERUM 1204 H
TRANSFERRIN 149 L
Non-reactive HIV-1


PHYSICAL
Lower abdominal pain daily, headaches (low grade) daily, malaise.


EVALUATION

How serious and urgent a medical risk does this current condition suggest?

What blood tests and non-invasive diagnostic tests would you order?

Specify what suspected medical diseases could be indicated?

Does this medical condition require a specialist in Gastroenterology & Hepatology and/or Hematology & Oncology? - EastCoast 2-8-04
Comment:  To answer your questions:
1) The labs are significant for marked anemia, elevated bilirubin and liver function tests, and markedly elevated ferritin. With a blood level that low, I would suggest an evaluation by your primary care provider to appropriately treat this and diagnose the cause.

2) Next tests would be an abdominal ultrasound (to evaluate the elevated liver tests and elevated bilirubin) and a hepatitis panel. With a ferritin that high, I would also consider a liver biopsy and genetic testing for hemochromatosis.

3) There are many diseases that can present this way. Any liver or gall bladder disorder, such as gall stones or hemochromatosis can present with these findings. With a low blood count, I would also look for GI causes of blood loss - a colonoscopy would be a reasonable first test.

4) A GI specialist would be the most pressing referral. For the anemia, a hematologist can be consulted for further guidance.

Follow up with your personal physician is essential.

This answer is not intended as and does not substitute for medical advice - the information presented is for patient education only. Please see your personal physician for further evaluation of your individual case.

Thanks,
Kevin, M.D.

Forum-M.D.-KYP
(10-Feb-04)

Comment 2

It looks like you may have some liver disease. Your ALT & AST are slightly elevated and your bilirubin is pretty high. You are also quite anemic. See a doctor ASAP.  -Caroline5 2-9-04

 

Comment 3:  I was wondering what kind of work you do?

The red blood cell anemia and concern for liver are a couple of symptoms of exposure to a chemical which is common place in businesses that deal with cleaning, oil cleanup, painting, and the like.

(I came to the forum to see what SGPT number of 7 means for a man when 30-65 is normal, and the concern seems to be for high numbers, not low)

Often the red blood cells need to be tested for RETIC ratio because they may be low functioning, and you may not have full blown hemolytic anemia, but you might have compensating hemolytic anemia. (As long as the bone marrow can replace the prematurely dying off red blood cells, the hemolysis won't show up in the blood counts) It does look like you have the blood counts showing something, though.

Did you work on the Exxon Valdez oil spill cleanup? You are about the right age. And the chemical they used in Inipol EAP 22 or Corexit were too strong with 2-butoxyethanol (AKA ethylene glycol monobutyl ether) OR were you a gulf war vet? They were exposed to this solvent and also the more complex diethylene glycol monobutyl ether. Fatigue is primary on their list of 'gulf war syndrome' symptoms. These chemicals are classified not only as solvents, but also as pesticides by EPA and they do cause endocrine disruption; they are also poisons. They are teratogens; they cause birth defects and with enough exposure you can have zero sperm. The list is a mile long of the harm to people; there already exist many people groups harmed who have the long term effects; they need to be medically monitored. - 'Mother Margaret' 2-28-04

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Questions and Answers SGPT  - http://www.medhelp.org/HealthTopics/SGPT.html