No we have many generations chemically poisoned
| Lower levels of glutathione
linked to autism
By David Liu
Apr 3, 2005, 15:11
A new study suggested that excessive cellular oxidative stress may be a factor causing autism.
In the study, researchers measured plasma glutathione and its metabolic precursors in 95 autistic children and 75 children without autism. It was found that levels of glutathione are significantly lower in autistic children than in the children without autism.
Glutathione is a key detoxifying compound in cells. The researchers believed that deficiency of glutathione cause excessive oxidative stress because the cells cannot deal with the damaging free radials adequately. The excessive free radials can damage the sensitive cells in the brain, the gastrointestinal tract, and the immune system, which eventually contribute to the development of autism.
Further studies suggested that three genes, namely, the catecho-O-methyltransferase gene, the transcobalamin II gene, and the glutathione-S-transferase M1 gene, may be affected somehow in the autistic children. It's not clear how these genes are involved in the autistic metabolic disorder. <more>
Some have suggested this is why mercury is more of a problem for some people.
I have been hearing about such dangers...
Here is information for consumers:
Shared by liberalnurse
Evidence for linkage on chromosomes 21q and 7q in a subset of autism
Researchers of the Cincinnati Children's Hospital Medical Center found that regions of two chromosomes are linked to susceptibility for a type of autism characterized by regression in development.
Developmental regression can include the loss of previously acquired language, social skills or both.
Moreover, the study is the first to identify involvement of chromosome 21 in this type of autism.
This may explain the increased prevalence of autism spectrum disorders ( ASD ) among children with Down syndrome, who have an extra copy of chromosome 21 and are 10 times more likely to have an ASD than the general population.
The findings represent " the important first step in identifying genetic variants that may contribute to susceptibility to this specific type of ASD, " says Cindy Molloy, lead author of the study.
The study is published in the Molecular Psychiatry.
Molloy and colleagues examined a U.S. database and DNA bank of hundreds of families with autism spectrum disorders.
They identified 32 pairs of siblings, one trio of siblings and one pair of cousins who showed definite evidence of regression at the age of approximately 18 to 24 months.
Researchers confirmed previous evidence for linkage with ASD on chromosome 7 and found new evidence for susceptibility on chromosome 21 in this subset of ASD families.
The research team is now sequencing genes in those regions to find the specific genetic variant that either contributes to susceptibility or modifies the disease.
"Among children with autism or autism spectrum disorders, 20 to 30 percent have a history of regression," says Molloy. " We think this represents a genetically distinct subgroup."
Autism is a complex developmental disability that affects an individual in the areas of social interaction and communication.
Autism is a spectrum disorder that affects each individual differently and to varying degrees of severity.
As many as 1.5 million Americans - children and adults - are thought to have autism today, according to the Autism Society of America.
Source: Cincinnati Children's Hospital Medical Center, 2005
we have multiple generations that are chemically poisoned
by a teratogen chemical