RISK is the Determining Factor! * (Lay Version*)
Remember that "all things are toxic and that it is the dose that makes the poison".
In this agency we take the above as gospel. Our focus therefore is on RISK.
Risk is always the qualifier when confronted with "is it safe?" questions. The answer must contain the words "when used as directed".
In this case I would say that if proper clothing and breathing apparatus was used, and if proper post-operational prophylaxis was followed then the RISK of adverse human effect would be very small.
IDENTIFICATION: 2-Butoxyethanol is a high production volume glycol ether. It is a colorless liquid that
is miscible in water and soluble in most organic solvents. 2-Butoxyethanol is used widely as a solvent in
surface coatings, such as spray lacquers, quick dry lacquers, enamels, varnishes, varnish removers and latex
paint. HUMAN EXPOSURE: Based on limited data, ambient exposures in air are generally in the ug/cu m
range. Industrial exposure of the general population to this chemical is most likely from inhalation and dermal
absorption during the use of products containing 2-butoxyethanol. Levels of airborne 2-butoxyethanol in
occupational settings are typically in the mg/cu m range. The results of in vitro studies indicate that human
red blood cells are not as sensitive to the hemolytic effects of 2-butoxyethanol and 2-butoxyacetic acid
and also that red blood cells are more sensitive to hemolysis by 2-butoxyacetic acid than to hemolysis by
2-butoxyethanol. ANIMAL STUDIES: 2-Butoxyethanol is readily absorbed following inhalation, oral or
dermal exposure. The chemical is metabolized via alcohol and aldehyde dehydrogenases, with the formation
of 2-butoxyacetaldehyde and 2-butoxyacetic acid, the principal metabolite, although other metabolic
pathways have also been identified. This chemical has moderate acute toxicity and it is irritating to the eyes
and skin; it is not a skin sensitizer. The principal effect exerted by 2-butoxyethanol and its metabolite
2-butoxyacetic acid is hematotoxicity, with the rat being the most sensitive species. In rats, adverse effects
on the central nervous system, kidneys and liver occur at higher exposure concentrations than do the
hemolytic effects. In animals, adverse effects on reproduction and development have not been observed at
less than toxic doses. Although the results of in vitro tests for mutagenicity of 2-butoxyethanol were
inconsistent, the absence of structural alerts and the negative findings from in vivo studies indicate that
2-butoxyethanol is not mutagenic.
[World Health Organization/International Programme on Chemical Safety. Concise
International Chemical Assessment Document No. 10. 2-Butoxyethanol p.4
From: firstname.lastname@example.org [mailto:email@example.com]
Sent: Wednesday, September 11, 2002 3:07 PM
To: Prince, George R.
Subject: OK except for 2-butoxyethanol?
So, when time permits, would it be your opinion that all the ingredients in inipol EAP 22 would be OK?
...except, of course for 2-butoxyethanol... which is not (causes hemolytic anemia, central nervous system damage, kidney, liver problems... most likely cancers)
Oleic Acid - primary ingredient
CAS Nr 112-80-1
OP's of this size will not be very soluble at all. -per chemist
10-12% of product by weight
Per its own MSDS: This substance may be hazardous to the environment; special attention should be given to the water environment and aquifer.
Urea CAS Nr 57-13-6
HO-C2H4-O-C4H9 ? same as:
Phosphorus source and surfactant
Surfactant & emulsion stabilizer or ... ?
Are any of the above no more than soap?
... like soap? emulsifier (softener) and surfactant (scrubber)