Also - NJ Hazardous Substance Fact Sheet 2-BUTOXY ETHANOL pdf
An Excellent help in understanding the Surfactant
of Inipol EAP 22 & Now Corexit 9500 & Corexit 9527?
Take this with you when you see your doctor,
along with all the other chemicals your compound of concern contains: * such as Inipol EAP 22
What 'package of symptoms' would you have? What other worker groups could be affected?
Categorized as a Poison 
- UN Hazard List *
CICA *
Detailed info *
& more *
Look for Autoimmune Hemolytic Anemia such as 2-butoxyethanol causes
10-19-04 Links added These SymptomsFeedback e-mail
Consider the points of attack (liver, kidneys, lymphoid system, skin,
blood, eyes, respiratory system) in placement and periodic physical
examinations.
[Sittig, M.
Handbook of Toxic and Hazardous Chemicals and Carcinogens, 1985. 2nd ed. Park
Ridge, NJ: Noyes Data Corporation, 1985. 155]**PEER REVIEWED**
2-Butoxyethanol
causes acute hemolytic anemia in rats
In F344
male rats, 2-butoxyethanol
causes severe acute hemolytic anemia resulting in significant increase in the
concentration of free plasma hemoglobin. Secondary to the hemolytic effects,
2-butoxyethanol
also caused hemoglobinuria as well as histopathologic changes in the liver and
kidney.
*Notes to Physician: Administration of Sodium bicarbonate may be of value to treat acidosis.
Monitor kidney and liver function and arterial blood gases closely.
More information on symptoms of overexposure to chemicals, in general, plus 2-butoxyethanol concerns
Synonyms: Butyl cellosolve®; Ethylene glycol monobutyl ether
CAS No.: 111-76-2
Molecular Weight: 118.18
Chemical Formula: HOCH2CH2OC4H9 ... actually C6H14O2/CH3(CH2)2CH2OCH2CH2OH
Product Codes:
J.T. Baker: D648, D649
Mallinckrodt: 2138
Ingredient CAS No Percent Hazardous --------------------------------------- ------------ ------------ --------- 2-Butoxyethanol 111-76-2 99 - 100% Yes
Emergency Overview
--------------------------
DANGER! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES EYE IRRITATION. AFFECTS CENTRAL NERVOUS SYSTEM, BLOOD AND BLOOD-FORMING ORGANS, KIDNEYS, LIVER AND LYMPHOID SYSTEM. COMBUSTIBLE LIQUID AND VAPOR. MAY CAUSE IRRITATION TO SKIN AND RESPIRATORY TRACT.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 2 - Moderate
Flammability Rating: 2 - Moderate
Reactivity Rating: 1 - Slight
Contact Rating: 3 - Severe (Life)
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD; PROPER GLOVES; CLASS B EXTINGUISHER
Storage Color Code: Red (Flammable)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to the respiratory tract. Symptoms may include sore throat, coughing, headache, nausea and shortness of breath. High concentrations have a narcotic effect.
Ingestion:
Causes irritation to the gastrointestinal tract. Symptoms may include nausea, vomiting and diarrhea. Toxic! May cause systemic poisoning with symptoms paralleling those of inhalation.
Skin Contact:
May cause irritation with redness and pain. May be absorbed through the skin with possible systemic effects.
Eye Contact:
Vapors are irritating and may produce immediate pain, redness and tearing. Splashes can cause severe pain, stinging, swelling.
Chronic Exposure:
Prolonged or repeated exposures can cause damage to the liver, kidneys, lymphoid system, blood and blood-forming organs.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders, eye problems, impaired liver, kidney, blood, respiratory or lymphoid system function may be more susceptible to the effects of the substance.
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician immediately.
Ingestion:
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Call a physician immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Call a physician, immediately. Wash clothing before reuse.
Eye Contact:
Immediately flush eyes with gentle but large stream of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Call a physician immediately.
Fire:
Flash point: 62C (144F)
Autoignition temperature: 238C (460F)
Flammable limits in air % by volume:
lel: 1.1; uel: 12.7
Combustible Liquid.
Explosion:
Above flash point, vapor-air mixtures are explosive within flammable limits noted above. Vapors can flow along surfaces to distant ignition source and flash back. Contact with strong oxidizers may cause fire. Sensitive to static discharge.
Fire Extinguishing Media:
Dry chemical, alcohol foam or carbon dioxide. Do not use a solid stream of water, since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool, dilute spills to nonflammable mixtures, protect personnel attempting to stop leak and disperse vapors.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
Ventilate area of leak or spill. Remove all sources of ignition. Wear appropriate personal protective equipment as specified in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from entering. Contain and recover liquid when possible. Use non-sparking tools and equipment. Collect liquid in an appropriate container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a chemical waste container. Do not use combustible materials, such as saw dust. Do not flush to sewer! If a leak or spill has not ignited, use water spray to disperse the vapors, to protect personnel attempting to stop leak, and to flush spills away from exposures.
J. T. Baker SOLUSORB® solvent adsorbent is recommended for spills of this product.
Protect against physical damage. Store in a cool, dry well-ventilated location, away from any area where the fire hazard may be acute. Outside or detached storage is preferred. Separate from oxidizing materials. Containers should be bonded and grounded for transfers to avoid static sparks. Storage and use areas should be No Smoking areas. Containers of this material may be hazardous when empty since they retain product residues (vapors, liquid); observe all warnings and precautions listed for the product.
Airborne Exposure Limits:
-OSHA Permissible Exposure Limit (PEL):
50 ppm skin
-ACGIH Threshold Limit Value (TLV):
20 ppm (TWA)
Ventilation System:
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):
If the exposure limit is exceeded and engineering controls are not feasible, a full facepiece respirator with organic vapor cartridge may be worn up to 50 times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres. This compound possibly exists in both particulate and vapor phase. A particulate (NlOSH type N95 or better) prefilter should be used for the particulate.
Skin Protection:
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Appearance:
Clear, colorless liquid.
Odor:
Mild odor.
Solubility:
Soluble in water.
Specific Gravity:
0.90 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
171C (340F)
Melting Point:
-70C (-94F)
Vapor Density (Air=1):
4.07
Vapor Pressure (mm Hg):
0.8 @ 20C (68F)
Evaporation Rate (BuAc=1):
0.07
Stability:
Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products:
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers, strong bases. May attack metallic aluminum at high temperatures.
Conditions to Avoid:
Heat, flames, ignition sources and incompatibles.
Toxicological Data:
Oral rat LD50: 470 mg/kg; Inhalation rat LC50: 450ppm/4H; Skin rabbit LD50: 220 mg/kg; investigated as a tumorigen, mutagen, reproductive effector
Reproductive Toxicity:
Has shown teratogenic effects in laboratory animals.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
2-Butoxyethanol (111-76-2) No No None
Environmental Fate:
When released into the soil, this material is not expected to evaporate significantly. When released into the soil, this material may leach into groundwater. When released into the soil, this material may biodegrade to a moderate extent. When released into water, this material is not expected to evaporate significantly. When released into water, this material may biodegrade to a moderate extent. This material has an estimated bioconcentration factor (BCF) of less than 100. This material is not expected to significantly bioaccumulate. When released into the air, this material is expected to be readily degraded by reaction with photochemically produced hydroxyl radicals. When released into the air, this material is expected to have a half-life of less than 1 day.
Environmental Toxicity:
The LC50/96-hour values for fish are over 100 mg/l. This material is not expected to be toxic to aquatic life.
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. (2-BUTOXYETHANOL)
Hazard Class: 6.1
UN/NA: UN2810
Packing Group: III
Information reported for product/size: 20L
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. (2-BUTOXYETHANOL)
Hazard Class: 6.1
UN/NA: UN2810
Packing Group: III
Information reported for product/size: 20L
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. (2-BUTOXYETHANOL)
Hazard Class: 6.1
UN/NA: UN2810
Packing Group: III
Information reported for product/size: 20L
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
2-Butoxyethanol (111-76-2) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
2-Butoxyethanol (111-76-2) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
2-Butoxyethanol (111-76-2) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
2-Butoxyethanol (111-76-2) No No Yes
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2R
Poison Schedule: None allocated.
WHMIS:
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.
NFPA Ratings: Health: 2 Flammability: 2 Reactivity: 0
Label Hazard Warning:
DANGER! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. CAUSES EYE IRRITATION. AFFECTS CENTRAL NERVOUS SYSTEM, BLOOD AND BLOOD-FORMING ORGANS, KIDNEYS, LIVER AND LYMPHOID SYSTEM. COMBUSTIBLE LIQUID AND VAPOR. MAY CAUSE IRRITATION TO SKIN AND RESPIRATORY TRACT.
Label Precautions:
Avoid breathing vapor or mist.
Avoid contact with eyes, skin and clothing.
Keep container closed.
Use only with adequate ventilation.
Wash thoroughly after handling.
Keep away from heat and flame.
Label First Aid:
In all cases call a physician immediately. If swallowed, induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. In case of contact, immediately flush eyes or skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last revision of document include: 8.
Disclaimer:
************************************************************************************************
Mallinckrodt Baker, Inc. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Environmental Health & Safety
Phone Number: (314) 654-1600 (U.S.A.)
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At one time source was http://www.jtbaker.com/msds/b6100.htm Actual Hazard Rating is not given on TSCA list * www.valdezlink.com/need.htm How to diagnose it's harm Check some of these basics
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