|
Immunoglobulin A, B, and M what are they?
|
March
04, 2004
Just a quick question for all the guru's out there. My value for
M was really low and highlighted in bold by the lab. The range
value is 40 to 230 and mine was 29 L. Just wondering what all
that means.
Headhunter25
CC |
March
05, 2004
From a definition found on the internet:
quote:
Immunoglobulin A Deficiency:
Synonyms and related keywords: immunodeficiency,
selective IgA deficiency, selective immunoglobulin A
deficiency, primary antibody deficiencies, primary antibody
deficiency, antibody deficiency, IgAD, immunodeficiency
disease, sinopulmonary infection, sinus infection, otitis
media, stomach cancer, Giardia lamblia, G lamblia,
Helicobacter pylori, H pylori, GI cancer, gastrointestinal
disease, GI disease, Crohn disease, upper respiratory tract
infection, lower respiratory tract infection, chronic
diarrhea, transfusion complication, blood product reaction,
adverse transfusion reaction
To continue: "Secretory IgA antibodies can neutralize
viruses, bind toxins, agglutinate bacteria, prevent bacteria
from binding to mucosal epithelial cells, and bind to various
food antigens, thus preventing their entry into the general
circulation. The role of serum IgA is unclear."
"IgAD is a primary immunodeficiency disease presumed to
result from a failure of terminal differentiation in IgA-positive
B cells. Multipotent hematopoietic stem cells give rise to
progenitors of T cells, B cells, and natural killer cells."
"The development of B-lineage cells begins in the fetal
liver. B-lineage cell development then transfers to the bone
marrow when it becomes the major hematopoietic organ. Pre–B
cells become immature immunoglobulin M (IgM)–positive B cells
and then migrate from the bone marrow to lymph node germinal
centers. After leaving the bone marrow, the B cells mature
and express immunoglobulin D receptors, respond to antigens,
and, with the help of T cells (CD4+), undergo proliferation and
plasma cell differentiation (International Union of
Immunological Societies, 1999)."
Source: www.emedicine.com/med/topic1159.htm
Mother
Margaret
|
March
05, 2004 <brownbassman100@aol.com>
I looked up some things on the internet about it. It is noted
that Immunoglobulin M deficiency is very rare. Less than 0.03%
of the international population. It is also fatal to infants,
young children and can be in adults. Maybe that's why I get
pluracy often? I get it almost every winter. I also wonder if
it's because I have mycoplasma infection in my body? I can't
understand why my nuero guy didn't pick up on this. My wife has
been in the hospitial for surgery so I went over my med recs
while waiting and saw it. Any info will be helpful.
Headhunter25
cc |
March
05, 2004
In sharing your question with 'Mike' his comments are:
"The immunoglobulin molecule: That's a rather complex
molecule! Well, the lymph nodes crank out this protein molecule
to go after foreign bodies in an organism.
Too low numbers found in a blood test just means that
particular means of defense is too low, possibly in decline.
Something is impeding the lymphs; bad nutrition, poisoning, old
age, etc. Trick is to discover what caused such a condition.
I suspect you're on the path to connect that ester-alcohol
solvent C6H14O2/CH3(CH2)2CH2OCH2CH2OH to lymph damage. Since the
liver is definitely damaged with that substance just like
longterm metalysis of ethanol, follows other organs will suffer
as well."
I met Mike Simmons when he gave permission to use some of his
'pianodude' music to the
website I was working on.
Then he added this www.valdezlink.com/media-ak/Exxon_Valdez_Movie.swf
Turns out he knows about various chemicals and their effects,
too!
Mother
Margaret
|
March
07, 2004
larrypam1010@sbcglobal.netcglobal.net>
Then someone explain to me Igg. Had high Igg to epstien barr
960, and high Igg to herpes 1 or 2 600+. I was told these are
intibodies to the viruses. And that Igm would indicate current
active infection.
Pam
|
March
07, 2004
Pam, is this the same thing?
quote:
IgG: Immunoglobulin G, a major class of immunoglobulins
found in the blood, including many of the most common
antibodies circulating in the blood. Also known as gamma
globulin.
MERCK medical dictionary has some pretty good definitions, check
this chapter on immune: THE
MERCK MANUAL, Sec. 12, Ch. 146, Biology Of The Immune System
and
THE
MERCK MANUAL, Sec. 11, Ch. 145, Aids-Associated Hematologic
Disorders And Malignancies
If the level is high, then your immune system is doing pretty
well? You can help everyone out by checking into it and letting
us know if you learn something more
Mother
Margaret |
March
07, 2004
PS
Could this be an autoimmune thing going on?
If your system is out of balance, such as what I expect to be
found eventually for those with hemolytic anemia from
2-butoxyethanol or diethylene glycol monobutyl ether ...
I would expect it to be diagnosed as acquired autoimmune
hemolytic anemia
Mother
Margaret |
March
09, 2004
2-Butoxyethanol is Butyl Cellosolve (trademark of Union
Carbide/Dow Chemical)
diethylene glycol monobutyl ether is Butyl Carbitol (Trademark
of ")
They are both solvents, but are chemically different.
Here's a link to the MSDS, if you need help understanding
MSDS or Toxicology let me know.
http://hazard.com/msds/
Just type in the product or chemical name and the search will
do the rest.
My boss, a chemist, gave me the URL and will explain anything
I do not understand.
Thanks
rh8x <rh8x@hotmail.com>
|
March
09, 2004
Great! Do you have time to look up diethylene glycol monobutyl
ether?
This is all I know about
it and here you note the original
source showing that the Gulf War troops were exposed to it
too .... I've found some synonyms, as well; they are probably
the same and more.
I got a lot of help from some chemists
when I first started learning about
2-butoxyethanol
Seems like 2(2-buotyxethanol) would be twice as bad
C6H14O2/CH3(CH2)2CH2OCH2CH2OH
Reproductive & Fetal Effects; Liver & Kidney Damage;
Blood Damage only Health Hazard level #2?
or
C8H18O3 / CH2(CH2)3OCH2CH2OCH2CH2OH
Kidney damage; Central Nervous System effects only Hazard
level 1?
CA & EPA study
Here are products that contain them that people use regularly
- Some are Not safe, wouldn't you agree? www.valdezlink.com/household112-34-5.htm
www.valdezlink.com/2_butoxyethanol_in_these.htm
(I think we are on another thread, folks)
While we're on this topic, here is a
summary page I just did
Mother
Margaret
|
fair
use 3-9-04 www.gulfwarvets.com/ubb/Forum1/HTML/000153.html |